1,3,2-Dioxaborolane, 2-[4-[2-(4-chlorophenyl)ethynyl]phenyl]-4,4,5,5-tetramethyl- - Names and Identifiers
Name | 2-{4-[2-(4-Chlorophenyl)ethynyl]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Synonyms | 2-{4-[2-(4-Chlorophenyl)ethynyl]phenyl}-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 1,3,2-Dioxaborolane, 2-[4-[2-(4-chlorophenyl)ethynyl]phenyl]-4,4,5,5-tetramethyl-
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CAS | 1315281-10-7
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1,3,2-Dioxaborolane, 2-[4-[2-(4-chlorophenyl)ethynyl]phenyl]-4,4,5,5-tetramethyl- - Physico-chemical Properties
Molecular Formula | C20H20BClO2
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Molar Mass | 338.64 |
Density | 1.16±0.1 g/cm3(Predicted) |
Boling Point | 449.8±30.0 °C(Predicted) |
Storage Condition | Room Temprature |
Sensitive | Irritant |
MDL | MFCD16294534 |
1,3,2-Dioxaborolane, 2-[4-[2-(4-chlorophenyl)ethynyl]phenyl]-4,4,5,5-tetramethyl- - Introduction
2-{4-[2-(4-Chlorophenyl)ethynyl]phenyl}-4,4, 5,5-tetrathyl-1, 3,2-dioxaborolane (abbreviated as BODMA) is an organic boron compound. Here is some information about BODMA:
Nature:
-Appearance: BODMA is a colorless to pale yellow solid.
-Solubility: BODMA has good solubility in common organic solvents.
-Melting point and boiling point: The melting point of BODMA is about 84-86°C, and the boiling point is about 400°C.
-Density: The density of BODMA is approximately 1.06 g/mL.
Use:
- BODMA is an important organoboron reagent, which is widely used in cross-coupling reactions in organic synthesis, such as Suzuki coupling and Sonogashira coupling.
- BODMA is also used in the research of some drugs and materials, such as for the preparation of catalysts, fluorescent dyes and radiation therapy drugs.
Preparation Method:
-The preparation of BODMA is generally obtained by borane chemical reaction. First, 2-bromoacetylene and 4-boronic acid phenyl phenol are reacted to obtain an intermediate, then a substitution reaction of a halogen compound is performed, and finally BODMA is formed by an oxidation reaction.
Safety Information:
- BODMA has low toxicity and irritation under general use conditions, but basic laboratory safety measures are still needed.
-Avoid contact with skin, eyes and respiratory tract, and wear protective gloves, glasses and masks if necessary.
-Avoid contact with fire and light during use and storage, and avoid mixing with oxidants.
-Compliance with local waste management regulations during handling and disposal.
It should be noted that BODMA is a compound specifically used for laboratory research. Please ensure that you have relevant chemical knowledge and experimental skills before use, and comply with relevant safety procedures.
Last Update:2024-04-09 21:01:54